Search results for "Pierre Robin"

showing 8 items of 8 documents

Variable pulmonary manifestations in Chitayat syndrome: Six additional affected individuals

2020

Hand hyperphalangism leading to shortened index fingers with ulnar deviation, hallux valgus, mild facial dysmorphism and respiratory compromise requiring assisted ventilation are the key features of Chitayat syndrome. This condition results from the recurrent heterozygous missense variant NM_006494.2:c.266A>G; p.(Tyr89Cys) in ERF on chromosome 19q13.2, encoding the ETS2 repressor factor (ERF) protein. The pathomechanism of Chitayat syndrome is unknown. To date, seven individuals with Chitayat syndrome and the recurrent pathogenic ERF variant have been reported in the literature. Here, we describe six additional individuals, among them only one presenting with a history of assisted ventil…

Adultbronchomalacia2716 Genetics (clinical)hyperphalangismPediatricsmedicine.medical_specialtyAdolescent10039 Institute of Medical Genetics610610 Medicine & healthChitayat syndromeFingersYoung Adult03 medical and health sciences1311 Geneticsrespiratory distressExome SequencingGeneticsmedicineHumansMissense mutationGenetic Predisposition to DiseaseHallux ValgusRespiratory systemChildGenetics (clinical)030304 developmental biologyCHITAYAT SYNDROME0303 health sciencesPierre Robin SyndromebiologyRespiratory distressbusiness.industry030305 genetics & heredityFaciesmedicine.diseasebiology.organism_classificationPhenotype3. Good healthRepressor ProteinsValgusERFChild Preschoolulnar deviation570 Life sciences; biologyFemaleUlnar deviationBronchomalaciabusinessAmerican Journal of Medical Genetics Part A
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A case of femoral-facial syndrome in a patient with autism spectrum disorders.

2011

The Femoral hypoplasia - unusual facies syndrome (FHUF) or Femoral - facial syndrome (FFS) was at first described in 1975. Up to now about 60 cases have been reported. According to our knowledge only 4 cases have had congenital central nervous system's malformations, furthermore the main stages of psychomotor development are almost always reported as normal or slightly altered in early childhood. We describe the first case of autism spectrum disorders (ASD) in a patient with FFS, emphasizing that this rare association could be one of many unrecognized underlying features.

Craniofacial AbnormalitiesDiagnosis DifferentialMalePierre Robin SyndromeChild Development Disorders PervasiveChild PreschoolFemoral facial syndromeChild development disorders pervasive Diabetes gestational.HumansAbnormalities MultipleFemurSettore MED/39 - Neuropsichiatria InfantileMinerva pediatrica
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SEMI-AUTOMATIC VOLUMETRIC SEGMENTATION OF THE UPPER AIRWAYS IN PATIENTS WITH PIERRE ROBIN SEQUENCE

2014

Pierre Robin malformation is a rare craniofacial dysmorphism whose pathogenesis is multifactorial. Although there is some agreement in non-invasive treatment in less severe cases, the dispute is still open on cases with severe respiratory impairment. We present a semi-automatic novel diagnostic tool for calculating upper airway volume, in order to eventually address surgery in patients with Pierre Robin Sequence (PRS). Multidetector CT datasets of two patients and two controls were tested to assess the proposed method for ROI segmentation, upper airway volume computation and three-dimensional reconstructions. The experimental results show an irregular pattern and a severely reduced cross-s…

MalePathologymedicine.medical_specialtymultidetector CTJaccard indexMultidetector ctImaging Three-DimensionalSimilarity (network science)Multidetector Computed TomographyImage Processing Computer-AssistedMedicineHumansRadiology Nuclear Medicine and imagingIn patientSegmentationairway model reconstructionRobin SequencePierre Robin sequenceAnatomy Cross-SectionalPierre Robin Syndromebusiness.industryairways segmentationInfantGeneral MedicineOriginal ArticlesOrgan SizePIERRE ROBIN SEQUENCE MULTIDETECTOR CT3D renderingAirway ObstructionRegion growingCase-Control StudiesPharynxFemaleNeurology (clinical)LarynxAirwaybusinessNuclear medicineregion growing
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An edge-driven 3D region-growing approach for upper airway morphology and volume evaluation in patients with Pierre Robin sequence

2015

Abstract: Pierre Robin sequence (PRS) is a pathological condition responsible for a sequence of clinical events, such as breathing and feeding difficulties, that must be addressed to give the patient at least a chance to survive. By using medical imaging techniques, in a non-intrusive way, the surgeon has the opportunity to obtain 3D views, reconstruction of the regions of interest (ROIs), useful to increase understanding of the PRS patient’s condition. In this paper, a semi-automatic approach for segmentation of the upper airways is proposed. The implemented approach uses an edge-driven 3D region-growing algorithm to segment ROIs and 3D volume-rendering technique to reconstruct the 3D mode…

Pierre Robin sequence multidetector CT airways segmentation region growing 3D rendering airway model reconstructionInternational Journal of Adaptive and Innovative Systems
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APPLICATION OF AN AUTOMATIC COMPUTERIZED ALGORITHM FOR THE ANALYSIS OF UPPER AIRWAYS REDUCTION IN PATIENTS WITH PIERRE ROBIN SEQUENCE STUDIED BY MDCT

2010

Pierre Robin MDCT
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Fisioterapia elettromiograficamente assistita nella sindrome di Pierre Robin

2008

Settore MED/28 - Malattie Odontostomatologicheelettromiografia sindrome di Pierre Robin
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Sindrome di pierre-robin trattata con fisioterapia elettromiograficamente assistita: case report

2009

Pierre Robin syndrome is characterized by the triad: micrognathia, cleft palate and glossoptosis. This syndrome, which often undermines several organs and systems, is treated with a multidisciplinary approach that involves several specialists. The AA. present a case of Pierre Robin syndrome in neuromuscular rehabilitation by physiotherapy EMG-assisted. PMID:19445280[PubMed - indexed for MEDLINE]

Settore MED/28 - Malattie Odontostomatologichesindrome di pierre robin fisioterapia elettromiografia
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The ultra-thin bronchoscope in management of the difficult paediatric airway

1987

The use of an ultra-thin flexible fiberoptic bronchoscope with a single lumen diameter of 2.7 mm at the distal tip to assist intubation of paediatric patients with a difficult airway is reported. Two patients (ages 30 months and 18 months) with mandibular hypoplasia and one patient (three months) with the Pierre-Robin syndrome are reported. In each case two fiberoptic bronchoscopes were used. The first allowed introduction of topical local anaesthetic while the second and smaller one was used for tube placement.

medicine.medical_specialtymedicine.medical_treatmentBronchoscopyIntubation IntratrachealmedicineFiber Optic TechnologyHumansIntubationBronchoscopesPaediatric patientsPierre Robin Syndromemedicine.diagnostic_testbusiness.industryInfantGeneral MedicineTemporomandibular Joint Disordersmedicine.diseaseHypoplasiaSurgeryLumen DiameterBronchoscopesAnesthesiology and Pain MedicineChild PreschoolAnesthesiaPierre Robin syndromeFemalebusinessAirwayAnesthesia LocalCanadian Journal of Anaesthesia
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